Cognitive Reserve Relates to Functional Network Efficiency in Alzheimer’s Disease
نویسندگان
چکیده
منابع مشابه
Measures of cognitive reserve in Alzheimer's disease.
INTRODUCTION Cognitive reserve (CR), a hypothetical construct used to obtain information about cognitive aging, describes the capacity of the adult brain to cope with the effects of neurodegenerative processes. This study evaluated CR using a CR questionnaire (CRQ) and a set of variables (education, leisure activities, lifelong occupation) that inform CR. It also developed a CR index, validated...
متن کاملThe functional connectome of cognitive reserve
Cognitive Reserve (CR) designates the brain's capacity to actively cope with insults through a more efficient use of its resources/networks. It was proposed in order to explain the discrepancies between the observed cognitive ability and the expected capacity for an individual. Typical proxies of CR include education and Intelligence Quotient but none totally account for the variability of CR a...
متن کاملCognitive reserve in ageing and Alzheimer's disease.
The concept of cognitive reserve provides an explanation for differences between individuals in susceptibility to age-related brain changes or pathology related to Alzheimer's disease, whereby some people can tolerate more of these changes than others and maintain function. Epidemiological studies suggest that lifelong experiences, including educational and occupational attainment, and leisure ...
متن کاملEfficiency, capacity, compensation, maintenance, plasticity: emerging concepts in cognitive reserve.
Cognitive reserve (CR) is a concept meant to account for the frequent discrepancy between an individual's measured level of brain pathology and her expected cognitive performance. It is particularly important within the context of aging and dementia, but has wider applicability to all forms of brain damage. As such, it has intimate links to related compensatory and neuroprotective concepts, as ...
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Patients with Parkinson's disease (PD) typically present with motor symptoms, but non-motor symptoms, including cognitive impairment, autonomic dysfunction and neuropsychiatric symptoms, are usually also present, when looked for carefully. The objective of this paper is to provide an up-to-date, comprehensive review of two undecided issues about cognitive impairment in PD patients without demen...
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ژورنال
عنوان ژورنال: Frontiers in Aging Neuroscience
سال: 2018
ISSN: 1663-4365
DOI: 10.3389/fnagi.2018.00255